Gene information
Official symbol IL13
Official full name interleukin 13
Gene type protein-coding gene
Chromosome5q31.1
Alias symbolP600; IL-13; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Gene familyInterleukins
Resources
Entrez Gene 3596
HGNC HGNC:5973
Ensembl ENSG00000169194
Vega OTTHUMG00000059723
UCSC uc003kxj.2
GO terms: 132 records
GO Description Category LogP Number of genes Detail
GO:0001774 microglial cell activation GO Biological Processes -13.1367436 11 More
GO:0001775 cell activation GO Biological Processes -43.3738118 71 More
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001819 positive regulation of cytokine production GO Biological Processes -44.1872667 64 More
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002269 leukocyte activation involved in inflammatory response GO Biological Processes -12.6026553 11 More
GO:0002274 myeloid leukocyte activation GO Biological Processes -20.6988408 25 More
GO:0002637 regulation of immunoglobulin production GO Biological Processes -8.47662495 11 More
GO:0002639 positive regulation of immunoglobulin production GO Biological Processes -6.83160707 8 More
GO:0002694 regulation of leukocyte activation GO Biological Processes -32.0887020 60 More
GO:0002696 positive regulation of leukocyte activation GO Biological Processes -27.9249645 47 More
GO:0002697 regulation of immune effector process GO Biological Processes -33.2683521 48 More
GO:0002699 positive regulation of immune effector process GO Biological Processes -18.3926498 29 More
GO:0002700 regulation of production of molecular mediator of immune response GO Biological Processes -19.7615296 26 More
GO:0002702 positive regulation of production of molecular mediator of immune response GO Biological Processes -12.4206918 17 More
GO:0002703 regulation of leukocyte mediated immunity GO Biological Processes -18.0432682 27 More
GO:0002886 regulation of myeloid leukocyte mediated immunity GO Biological Processes -10.0272645 11 More
GO:0005125 cytokine activity GO Molecular Functions -54.7097150 57 More
GO:0005126 cytokine receptor binding GO Molecular Functions -41.4908940 50 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0009612 response to mechanical stimulus GO Biological Processes -18.7627330 44 More
GO:0009617 response to bacterium GO Biological Processes -52.1760880 83 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0010959 regulation of metal ion transport GO Biological Processes -23.6318171 71 More
GO:0017157 regulation of exocytosis GO Biological Processes -7.48561663 15 More
GO:0030545 signaling receptor regulator activity GO Molecular Functions -87.4728446 102 More
GO:0030546 signaling receptor activator activity GO Molecular Functions -90.4065983 101 More
GO:0030856 regulation of epithelial cell differentiation GO Biological Processes -15.4645914 35 More
GO:0030857 negative regulation of epithelial cell differentiation GO Biological Processes -6.09984616 12 More
GO:0030858 positive regulation of epithelial cell differentiation GO Biological Processes -9.94639997 18 More
GO:0030888 regulation of B cell proliferation GO Biological Processes -7.97568198 10 More
GO:0030890 positive regulation of B cell proliferation GO Biological Processes -8.50618951 9 More
GO:0031341 regulation of cell killing GO Biological Processes -10.2641102 14 More
GO:0031342 negative regulation of cell killing GO Biological Processes -3.33685104 4 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0031348 negative regulation of defense response GO Biological Processes -30.3795513 65 More
GO:0032102 negative regulation of response to external stimulus GO Biological Processes -54.2675416 110 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032653 regulation of interleukin-10 production GO Biological Processes -10.1959901 18 More
GO:0032733 positive regulation of interleukin-10 production GO Biological Processes -8.60591296 9 More
GO:0032944 regulation of mononuclear cell proliferation GO Biological Processes -24.6915018 34 More
GO:0032946 positive regulation of mononuclear cell proliferation GO Biological Processes -20.2231223 25 More
GO:0033003 regulation of mast cell activation GO Biological Processes -4.83325597 6 More
GO:0033005 positive regulation of mast cell activation GO Biological Processes -4.00389964 4 More
GO:0033006 regulation of mast cell activation involved in immune response GO Biological Processes -5.56777868 6 More
GO:0033008 positive regulation of mast cell activation involved in immune response GO Biological Processes -4.62139945 4 More
GO:0034762 regulation of transmembrane transport GO Biological Processes -31.7284805 100 More
GO:0034764 positive regulation of transmembrane transport GO Biological Processes -18.2616571 46 More
GO:0034765 regulation of ion transmembrane transport GO Biological Processes -18.4305966 71 More
GO:0034767 positive regulation of ion transmembrane transport GO Biological Processes -11.2867591 18 More
GO:0035094 response to nicotine GO Biological Processes -8.07167727 14 More
GO:0042116 macrophage activation GO Biological Processes -15.3664951 15 More
GO:0042509 regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.4049069 20 More
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein GO Biological Processes -19.8380655 19 More
GO:0043030 regulation of macrophage activation GO Biological Processes -14.6396218 15 More
GO:0043032 positive regulation of macrophage activation GO Biological Processes -14.1432953 16 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0043269 regulation of ion transport GO Biological Processes -36.9814668 116 More
GO:0043270 positive regulation of ion transport GO Biological Processes -23.5832054 34 More
GO:0043300 regulation of leukocyte degranulation GO Biological Processes -5.75997337 7 More
GO:0043302 positive regulation of leukocyte degranulation GO Biological Processes -3.69512980 4 More
GO:0043304 regulation of mast cell degranulation GO Biological Processes -5.73056952 6 More
GO:0043306 positive regulation of mast cell degranulation GO Biological Processes -4.62139945 4 More
GO:0045321 leukocyte activation GO Biological Processes -25.4958219 48 More
GO:0045471 response to ethanol GO Biological Processes -15.9991788 20 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045921 positive regulation of exocytosis GO Biological Processes -5.75584660 9 More
GO:0048018 receptor ligand activity GO Molecular Functions -91.0736151 101 More
GO:0048145 regulation of fibroblast proliferation GO Biological Processes -11.1167439 21 More
GO:0048146 positive regulation of fibroblast proliferation GO Biological Processes -7.96091962 9 More
GO:0048660 regulation of smooth muscle cell proliferation GO Biological Processes -48.6624498 69 More
GO:0048661 positive regulation of smooth muscle cell proliferation GO Biological Processes -29.0732096 40 More
GO:0050670 regulation of lymphocyte proliferation GO Biological Processes -22.6006415 32 More
GO:0050671 positive regulation of lymphocyte proliferation GO Biological Processes -19.1485102 24 More
GO:0050708 regulation of protein secretion GO Biological Processes -30.3716714 63 More
GO:0050714 positive regulation of protein secretion GO Biological Processes -15.7339081 32 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050728 negative regulation of inflammatory response GO Biological Processes -31.0556128 55 More
GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.1120967 60 More
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO Biological Processes -27.9747849 34 More
GO:0050778 positive regulation of immune response GO Biological Processes -17.2528761 40 More
GO:0050864 regulation of B cell activation GO Biological Processes -7.98662389 16 More
GO:0050865 regulation of cell activation GO Biological Processes -40.6877761 71 More
GO:0050867 positive regulation of cell activation GO Biological Processes -31.2431659 51 More
GO:0050871 positive regulation of B cell activation GO Biological Processes -8.77049404 15 More
GO:0051046 regulation of secretion GO Biological Processes -54.0079540 130 More
GO:0051047 positive regulation of secretion GO Biological Processes -32.2282376 71 More
GO:0051222 positive regulation of protein transport GO Biological Processes -13.8994291 46 More
GO:0051223 regulation of protein transport GO Biological Processes -25.2801266 81 More
GO:0051249 regulation of lymphocyte activation GO Biological Processes -22.6120519 46 More
GO:0051251 positive regulation of lymphocyte activation GO Biological Processes -20.2181987 37 More
GO:0051279 regulation of release of sequestered calcium ion into cytosol GO Biological Processes -5.25087734 14 More
GO:0051282 regulation of sequestering of calcium ion GO Biological Processes -7.93009971 22 More
GO:0051341 regulation of oxidoreductase activity GO Biological Processes -18.1249013 32 More
GO:0051354 negative regulation of oxidoreductase activity GO Biological Processes -6.94413823 11 More
GO:0051924 regulation of calcium ion transport GO Biological Processes -18.2498286 49 More
GO:0051928 positive regulation of calcium ion transport GO Biological Processes -8.94961635 14 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0061900 glial cell activation GO Biological Processes -13.6981492 12 More
GO:0070201 regulation of establishment of protein localization GO Biological Processes -24.4831554 82 More
GO:0070663 regulation of leukocyte proliferation GO Biological Processes -26.8242532 37 More
GO:0070665 positive regulation of leukocyte proliferation GO Biological Processes -21.5362473 27 More
GO:0071214 cellular response to abiotic stimulus GO Biological Processes -11.2775864 23 More
GO:0071260 cellular response to mechanical stimulus GO Biological Processes -11.7214175 13 More
GO:0071345 cellular response to cytokine stimulus GO Biological Processes -39.647808 70 More
GO:0071496 cellular response to external stimulus GO Biological Processes -17.0078490 52 More
GO:0071634 regulation of transforming growth factor beta production GO Biological Processes -6.40741477 11 More
GO:0071635 negative regulation of transforming growth factor beta production GO Biological Processes -3.34912948 3 More
GO:0097305 response to alcohol GO Biological Processes -17.4096682 46 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0104004 cellular response to environmental stimulus GO Biological Processes -11.2775864 23 More
GO:0120161 regulation of cold-induced thermogenesis GO Biological Processes -19.1025541 38 More
GO:0120162 positive regulation of cold-induced thermogenesis GO Biological Processes -19.5569802 32 More
GO:0150076 neuroinflammatory response GO Biological Processes -13.2187099 12 More
GO:1901214 regulation of neuron death GO Biological Processes -23.5458880 37 More
GO:1901215 negative regulation of neuron death GO Biological Processes -19.0527525 45 More
GO:1903169 regulation of calcium ion transmembrane transport GO Biological Processes -8.80532519 28 More
GO:1903305 regulation of regulated secretory pathway GO Biological Processes -6.01402466 11 More
GO:1903307 positive regulation of regulated secretory pathway GO Biological Processes -2.97443173 8 More
GO:1903530 regulation of secretion by cell GO Biological Processes -45.6472055 114 More
GO:1903532 positive regulation of secretion by cell GO Biological Processes -27.9542102 63 More
GO:1903829 positive regulation of protein localization GO Biological Processes -12.9651258 57 More
GO:1904035 regulation of epithelial cell apoptotic process GO Biological Processes -21.2824424 33 More
GO:1904036 negative regulation of epithelial cell apoptotic process GO Biological Processes -12.0631217 12 More
GO:1904062 regulation of cation transmembrane transport GO Biological Processes -18.6629834 61 More
GO:1904064 positive regulation of cation transmembrane transport GO Biological Processes -10.8655330 17 More
GO:1904427 positive regulation of calcium ion transmembrane transport GO Biological Processes -4.11465146 13 More
GO:1904951 positive regulation of establishment of protein localization GO Biological Processes -13.0308630 46 More
GO:2000351 regulation of endothelial cell apoptotic process GO Biological Processes -18.6276983 25 More
GO:2000352 negative regulation of endothelial cell apoptotic process GO Biological Processes -10.8868003 10 More
KEGG pathways: 8 records
KEGG Description Category LogP Number of genes Detail
hsa04060 Cytokine-cytokine receptor interaction KEGG Pathway -61.0014447 66 More
hsa04630 JAK-STAT signaling pathway KEGG Pathway -14.4088859 21 More
hsa04657 IL-17 signaling pathway KEGG Pathway -16.8039621 19 More
hsa04658 Th1 and Th2 cell differentiation KEGG Pathway -5.18694144 15 More
hsa04664 Fc epsilon RI signaling pathway KEGG Pathway -4.79120438 7 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05310 Asthma KEGG Pathway -7.19451595 7 More
hsa05321 Inflammatory bowel disease KEGG Pathway -16.3800424 16 More
Drug-Gene interaction
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Related drugs: 8 records
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
NM_002188.3:c.431A>G genomics myocardial infarction[diagnosis] myocardial infarction Xenophontos S et al. Open Cardiovasc Med J. 2008
interleukin-13 proteomics left ventricular remodeling[prognosis (bad)] ST elevation myocardial infarction Parisi V et al. Front Physiol. 2020
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